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The N4/N20 Zurich west bypass, in Knonaueramt, Switzerland, is 24 km long, of which some 13.5 km are tunnels. The Islisbergtunnel, the last of five tunnels, rounded off the work on the west bypass in 2009 - pleasing inhabitants of the area, commuters, and tourists. Through traffic was greatly reduced in nearby areas with its opening.

Safety, operation, cost-effectiveness, and high availability in the tunnel

Monitoring and operating a tunnel are very complex tasks. The challenges facing the operating and safety equipment are demanding. Parts of the system need to communicate with each other seamlessly and consistent operation of tunnel systems is an absolute must.

Pöyry Infra AG, a Zurich-based renowned planning firm in the infrastructure sector with around 280 engineers and specialists, took on the planning, organization, and implementation of this challenging task.

Particular value was placed on the planning and implementation of modern, future-oriented technology and products. The entire order for supplying electromechanical components for distributed I/O devices was placed with Phoenix Contact thanks to the company's good reputation. Bus couplers and I/O modules for parts of the operating and safety equipment were among the devices ordered.

Phoenix Contact products had previously been used and tested in other projects, such as the Kirchenwald tunnel. The impressive component performance, as well as the advice and support received from Phoenix Contact employees finally led to the implementation of our technology throughout the length of the tunnel.

Phoenix Contact components were implemented in many areas of the west bypass - tunnel airing and ventilation, lighting, power supply for the control room and emergency systems such as safety door control.

A higher-level control system controls the modules used from a central location. Airing and ventilation in the tunnel is carried out via the distributed I/O modules used in the Inline system kit. This enables easy conversion or replacement without any need to interrupt operation.

The QUINT POWER power supply units are suitable for universal and worldwide use thanks to the wide-range input of 85 to 264 V AC. Even in the event of power failures up to 20 ms, QUINT POWER still provides the full output. To this end, Power Boost controls preventive function monitoring via the power reserve, thereby ensuring an uninterrupted power supply.

The availability of all components is significantly increased by using surge arresters.

In the Kirchenwald tunnel project, the connection doors can be safely opened and closed in the event of an emergency, using safety devices from the PSR product range.

The tunnels in both directions are connected via a cross passage, enabling access for rescue in the case of emergency through the unaffected tunnel - this tunnel, however, must always be kept closed.

Phoenix Contact supports the most important functionalities in the tunnel system, such as safety, operation, cost-effectiveness, and availability. Different products are used to meet these goals, including PROFIBUS converters, programmable logic controllers (PLCs), bus couplers, DIN rail-mountable power supply units, thermomagnetic circuit breakers, and surge protection.

When building the Zurich west bypass, particular attention was always placed on continuing cooperation and ongoing technical development. In this way, an efficient solution was found and implementation was a success.

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List is meant to aid "transparency", FDA says
by Maggie Fox /
Get breaking news alerts and special reports. The news and stories that matter, delivered weekday mornings.

The Food and Drug Administration publicly outed brand name drugmakers Thursday for making it harder for generic drug companies to make cheaper copies of their products.

The FDA list includes more than 50 drugs that have been named in queries from generics makers — many of them complaints about obstacles to getting samples so they can copy them.

FDA commissioner Dr. Scott Gottlieb denied he was trying to shame pharmaceutical companies but said the public discussion can make things a little more transparent.

The FDA is framing the move as part of the administration’s effort to bring down drug prices.

“No patients should be priced out of medicines they need to support their health,” Gottlieb said in a statement. “We hope that this increased transparency will help reduce unnecessary hurdles to generic drug development and approval.”

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Drug companies are free to charge whatever they want for their products. When a company invents a new drug, it can patent it. The FDA also gives drugs exclusivity to prevent competition for various periods of time.

When that exclusivity period is up, the companies have to submit to competition from generic copies.

But drugmakers often do what they can to prevent this, sometimes by tweaking drug and by getting them approved for various new conditions. And, the FDA said, sometimes they try to stop competitors from getting samples to copy.

“At times, certain ‘gaming’ tactics have been used to delay generic competition,” the FDA said in a statement.

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Big Pharma spends millions to squelch drug price talk

“One example of such gaming is when potential generic applicants are prevented from obtaining samples of certain brand products necessary to support approval of a generic drug. The inability of generic companies to purchase the samples they need slows down, or entirely impedes, the generic drug development process – leading to delays in bringing affordable generic alternatives to patients in need.”

Some of the drugs on the list have had only a handful of inquiries but Letairis, a drug sold by Gilead Sciences to treat a condition called pulmonary arterial hypertension, got 10 queries. Cancer drug Revlimid, made by Celgene, was the subject of 13 letters, while Actelion’s Tracleer, another pulmonary arterial hypertension drug, is named 14 times.

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